Black-Suited Spider-Man (Sandman Series)
"His mind infected by the thoughts of an alien symbiote and his strength enhanced by the creature that clings to his skin, Spider-Man feels an uncharacterstic rage taking him over. His best friend is trying to kill him, his girlfriend is unimpressed with his strange, new powers, and his Uncle Ben's real killer has shown his face. The world is out to get him; all you have to do to see that is look at the front page of the Bugle. Well if the world wants to think of him as a dangerous vigilante, then that's what they'll get, and Sandman is going to be the first to get a personal taste.
Includes the left leg of Sandman."